47 results
Idiopathic Thrombocytopenic Purpura 
Clinical:
 • Gingival 
 • Menorrhagia 
 • GI bleeding 
 • Intracranial
Purpura Clinical ... children) • Platelets ... extremely low platelet ... #Purpura #Thrombocytopenia ... Diagnosis #Overview #Hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... inflammation • Thrombocytopenia ... Primary Causes: - Thrombocytopenia ... #Differential # ... #nonpalpable #dermatology
Causes of Purpura - Differential Diagnosis
Disruption in Vascular Integrity: 
 • Trauma, Infection, Vasculitis, Drug induced
- Differential ... collagen vascular disorders ... Primary hemostasis: Thrombocytopenia ... , Platelet dysfunction ... palpable #Causes #Differential
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
for workup of thrombocytopenia ... purpura/hemolytic ... , Hematology 2012 ... #Diagnosis #Differential ... #Algorithm #Thrombocytopenia
Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH 

These rashes can be especially challenging and are
associated with devastating differential
with devastating differential ... presents in thrombocytopenic ... palpable, the differential ... #Diagnosis #Dermatology ... #Nonpalpable #Differential
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
receptor] • Thrombocytopenia ... MYH9-Related Disorder ... chain IIA • Thrombocytopenia ... comparison #table #differential ... #diagnosis #hematology
Drug-Induced Thrombocytopenia
The diagnosis of drug-induced thrombocytopenia can be made only by demonstrating resolution of thrombocytopenia once
Drug-Induced Thrombocytopenia ... purpura. ... #Diagnosis #Hematology ... #Thrombocytopenia ... #Differential #
Thrombocytopenia - Differential Diagnosis Algorithm

Decreased production:
 • Bone marrow suppression
 • Bone marrow failure
 • Bone
Thrombocytopenia ... - Differential ... Connective tissue disorders ... #Differential # ... #platelets
Thrombocytosis - Differential Diagnosis
Platelet Count > 450
Reactive:
 • Anemia/blood loss (Fe deficiency)
 • Infection/Sepsis
 • Non-infectious
Thrombocytosis - Differential ... Diagnosis Platelet ... Myelofibrosis • Chronic Myeloid ... Thrombocytosis #Differential ... #hematology
Causes of Purpura or Easy Bruising in Children

Platelet count reduced, i.e. thrombocytopenia
 - Increased platelet destruction
Causes of Purpura ... purpura ... Congenital - Rare disorders ... bypass Vascular disorders ... pediatrics #diagnosis #differential