6 results
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Monoclonal Gammopathy ... (MGUS) - Differential ... #Gammopathy #Clinical ... #Diagnosis #hematology ... #oncology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral Infection Clinical ... younger pts) Differential ... Diagnosis Monoclonal ... gammopathy of undetermined ... , Myeloma • Waldenström
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
MGUS • Multiple myeloma ... Smoldering multiple myeloma ... • Plasma cell ... Gap #ProteinGap #differential ... #diagnosis #hematology
Solitary Cell Plasmacytoma

What?
• Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma)
• In 3%
Solitary Cell Plasmacytoma ... ) Clinical Presentation ... tissue composed of monoclonal ... Bone marrow Treatment ... Oncology #Diagnosis
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Lymphoma (HCV) • CLL ... POEMS (Sclerotic myeloma ... POEMS (Sclerotic myeloma ... #Monoclonal #Differential ... #Diagnosis #Oncology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
, or all three myeloid ... compounds, alcohol, lead ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology