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hematology monoclonal agglutinin anemia cell disease gammopathy hemolytic management mds myelodysplasia myelodysplastic plasmacytoma significance solitary syndrome syndromes vonwillebrand workup
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
POEMS (Sclerotic myeloma ... angioedema • vWD • acquired ... anemia due to cold ... #Differential # ... Diagnosis #Oncology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... Significance (MGUS ... ) - Differential ... Diagnosis #hematology ... #oncology
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Acquired von Willebrand ... lymphoma, multiple myeloma ... assist device (LVAD ... #Management #treatment ... #hematology #differential
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral Infection Clinical ... younger pts) Differential ... significance (MGUS ... ), CLL, Myeloma ... hemolytic #anemia #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
, or all three myeloid ... compounds, alcohol, lead ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
plasmacytoma) Clinical ... Bone marrow Treatment ... • Multiple myeloma ... #Plasmacytoma #Oncology ... #Hematology
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