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hematology management mds myelodysplastic syndrome workup agglutinin aplastic causes cell disease disorders hemolytic monoclonal paraproteinemias plasmacytoma platelet solitary syndromes thrombocytopenia
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic ... Management Summary myelo ... : 70 years old, ... cytopenias (usually anemia ... #hematology #oncology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
angioedema • vWD • acquired ... (-) hemolytic anemia ... due to cold IgG ... #Monoclonal #Differential ... #Diagnosis #Oncology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
anemia • Cold ... younger pts) Differential ... significance (MGUS ... ), CLL, Myeloma ... #hematology #diagnosis
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Acquired von Willebrand ... lymphoma, multiple myeloma ... assist device (LVAD ... #Management #treatment ... #hematology #differential
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
, or all three myeloid ... compounds, alcohol, lead ... blood count with differential ... #Syndromes #diagnosis ... #hematology #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Anticonvulsants - Gold ... • Hypocellular myelodysplastic ... Treatment: ... #oncology #hematology ... #diagnosis #management
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... practices that could ... HCV testing - Lab ... changes), high MCV anemia ... #Workup #hematology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
• No CRAB - no anemia ... Bone marrow Treatment ... • Multiple myeloma ... #Plasmacytoma #Oncology ... #Hematology
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