12 results
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... reticularis Differential ... • Goodpasture syndrome ... #dermatology #rash
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... • Tumor lysis syndrome ... lymphoid organs When Cancer ... -> Invade Skin: ... #Oncology #Diagnosis
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
- Rash: multiple ... Causes: - Idiopathic ... - Lupus - Leukemia ... #diagnosis #dermatology ... #oncology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Lymphoma (HCV) • CLL ... Alpha & Mu) Skin ... to cold IgG • Lupus ... #Monoclonal #Differential ... #Diagnosis #Oncology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... 3rd Decade Skin ... Disease Classification ... permanent alopecia Differential ... fibromyalgia) • Infections
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
> PR3 60% • GPA ... tract, and often causes ... mucositis - Rash ... to exclude are infections ... #classification
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... three myeloid hematopoiesis ... blood count with differential ... #diagnosis #hematology ... #oncology
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... : • Syndrome of ... disease, alcohol, cancer ... #differential # ... diagnosis #infectiousdiseases
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
gammopathy, and skin ... changes (POEMS syndrome ... Include: • Viral infections ... ovarian tumors, lung cancers ... #diagnosis #hematology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
(GCA) Giant cell ... Diagnosis = clinical ... vs infection vs ... required due to skip ... #Management