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hematology causes allergy cardiomyopathy eosinophil globulin immunology leukemia mds monoclonal myelodysplasia myelodysplastic paraproteinemias pathergy petechiae petechial physicalexam protein proteingap rash
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... symptoms (eg, skin ... #Disorders #Algorithm ... #Differential # ... diagnosis #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
activity • ↓ LAP ... • (Peripheral eosinophilia ... CLL -> Invade Skin ... #Leukemia #Hematology ... #Oncology #Diagnosis
Restrictive Cardiomyopathy - Diagnosis and Causes Clinical: Dyspnea, Exercise Intolerance, ↑ "Right Sided-Symptoms" (ascites, hepatomegaly, ↑↑peripheral edema) Physical
: Amyloidosis (AL ... Fibrosis, Hyper-eosinophilc ... Sarcomeric Protein Disorders ... #Causes #differential ... #cardiology #algorithm
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Alpha & Mu) Skin ... Episodic angioedema+eosinophilia ... Pseudohyponatremia • ↓anion gap ... #Monoclonal #Differential ... #Diagnosis #Oncology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Diagnosis Algorithm ... deficiency Work ... cryoglobulins • Skin ... #Diagnosis #Algorithm ... #Causes #dermatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... three myeloid hematopoiesis ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... gammopathy, and skin ... Connective tissue disorders ... #ProteinGap #differential ... #diagnosis #hematology
Pathergy Summary Overview What is pathergy? Pathergy is an exaggerated skin injury occurring after minor trauma such as
syndrome • Chronic myeloid ... interferon-alpha • Atypical eosinophilic ... Myeloproliferative disorders ... #differential # ... allergy #immunology #dermatology
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