9 results
Evaluation of Patients with Anemia

Microcytic, Normocytic, Macrocytic, Hemolytic (Intravascular and Extravascular)

#Diagnosis #Anemia #Workup #Macrocytic #Microcytic #Normocytic
Microcytic, Normocytic ... , Macrocytic, Hemolytic ... Extravascular) #Diagnosis ... #Anemia #Workup ... #Normocytic #Differential
Anemia - Workup and Differential Diagnosis
 - History, Physical Exam, Labs
 - Microcytic
 - Normocytic
 -
Anemia - Workup ... Exam, Labs - Microcytic ... - Normocytic ... Hemolytic #Anemia ... #Workup #Differential
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
- Differential ... Diagnosis Framework ... by MCV Microcytic ... Normocytic ( ... #Diagnosis #hematology
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... (up to 100) = normocytic ... acute blood loss, hemolysis ... #Workup #Hematology ... #Microcytic #Macrocytic
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
RBC) Morphology Microcytic ... lymphoma, Multiple myeloma ... Diseases #Red #BloodCell ... RBC #Morphology #differential ... #diagnosis #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Diagnosis: • hemolytic ... anemia • Cold ... younger pts) Differential ... significance (MGUS), CLL, Myeloma ... #anemia #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Volume (MCV) - Differential ... Diagnosis Algorithm ... Formation • Multiple Myeloma ... #elevatedMCV #Differential ... #Causes #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Agglutination - Cold agglutinins ... #Anemia #Differential ... #workup #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... , or all three myeloid ... Workup: • Complete ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis