10 results
Evaluation of Patients with Anemia

Microcytic, Normocytic, Macrocytic, Hemolytic (Intravascular and Extravascular)

#Diagnosis #Anemia #Workup #Macrocytic #Microcytic #Normocytic
Microcytic, Normocytic ... , Macrocytic, Hemolytic ... Extravascular) #Diagnosis ... #Anemia #Workup ... #Normocytic #Differential
Anemia - Workup and Differential Diagnosis
 - History, Physical Exam, Labs
 - Microcytic
 - Normocytic
 -
Anemia - Workup ... Exam, Labs - Microcytic ... - Normocytic ... Hemolytic #Anemia ... #Workup #Differential
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
- Differential ... Normocytic ( ... -100): • Non-hemolytic ... , CKD • Hemolytic ... #Diagnosis #hematology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Microangiopathic Hemolytic ... spherocytosis, Autoimmune hemolytic ... autoimmune hemolytic ... #differential # ... diagnosis #hematology
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Atlas • Microcytic ... spherocytosis, Hemolytic ... Schistocytes - Hemolytic ... #Atlas #key #diagnosis ... #differential #
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Diagnosis Algorithm ... Formation • Multiple Myeloma ... #Anemia #Macrocytosis ... #elevatedMCV #Differential ... #Causes #Hematology
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... (up to 100) = normocytic ... acute blood loss, hemolysis ... #Algorithm #Diagnosis ... #Workup #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... elliptocytosis, autoimmune hemolysis ... ARUPConsult @ARUPLabs #Hemolytic ... #Anemia #Differential ... #workup #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Diagnosis: • hemolytic ... • Compensated hemolysis ... intravascular hemolysis ... agglutinin #disease #hemolytic ... #anemia #hematology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
POEMS (Sclerotic myeloma ... • Coombs (-) hemolytic ... anemia due to cold ... #Monoclonal #Differential ... #Diagnosis #Oncology