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management rheumatology dementia encephalopathy gbs gravis guillain hiv immune inflammatory iris mds myasthenia myelitis myelodysplasia myelodysplastic neurocognitive oncology polychondritis posterior
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
Disorder (HAND) ... activation -> diffuse myelin ... Diagnosis: MRI ... #dementia #AIDS ... #Neurology
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... directed towards the myelin ... than one after symptom ... #Syndrome #diagnosis ... #management #neurology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
fluctuations PRES-Associated ... Etiology: • Pathophysiology ... Neurological symptoms ... Reversible course Differential ... Seizures: Treat with AEDs
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
an autoimmune disorder ... Associated with: ... Ocular- 50%: Ptosis ... life-threatening Differential ... #management #neurology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... , or all three myeloid ... changes that are associated ... blood count with differential ... #diagnosis #hematology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... /or symptoms • ... • Infectious causes ... vaccination - Myelin ... #differential
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... • Progressive symptoms ... VASCULITIS: ANCA Associated ... often causes arthritis ... #Diagnosis #Rheumatology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... treatment of HIV/AIDS ... be present: • AIDS ... Other Pathogens Associated ... albicans • Epstein Barr
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
body (Autoimmune disorder ... ethnicities Symptoms ... + Nonspecific symptoms ... chondritis • Ocular ... MDS & Multiple myeloma
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