9 results
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Pruritus - Generalized ... Systemic and Primary Causes ... renal failure/uremia ... Throbocythemia • Myelodisplastic ... #generalized #dermatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic ... Summary myelo ... old, ~10,000 new cases ... cytopenias (usually anemia ... #treatment #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... just beneath the skin ... , or all three myeloid ... blood count with differential ... Syndromes #diagnosis #hematology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm

Blood Glucose:
 • Diabetes Mellitus
Liver Function Tests/Enzymes:
Pruritus - No Primary ... Skin Lesion - Differential ... renal failure/uremia ... Throbocythemia • Myelodisplastic ... Diagnosis #Algorithm #causes
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Headaches • Pale skin ... and petechiae Causes ... • Hypocellular myelodysplastic ... #oncology #hematology ... #diagnosis #management
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... asymptomatic • Pruritus ... Examination: • Skin ... bile ducts Differential
Vibrio Vulnificus skin infection
Cirrhosis w/recent consumption of raw oysters w/rapidly evolving rash. 
Vibrio vulnificus part of
Vibrio Vulnificus skin ... infection Cirrhosis ... marine microbiota & causes ... hemochromatosis, hemolytic anemia ... legs #clinical #photo
Capnocytophaga Canimorsus Skin Rash

40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
Bandemia, AKI. ... dogs & latter can cause ... asplenia, alcoholism, cirrhosis ... persist → DIC, MODS ... #clinical #photo
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
MGUS • Multiple myeloma ... gammopathy, and skin ... Liver disease: Cirrhosis ... Thalassemia, Sickle cell anemia ... Gap #ProteinGap #differential