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algorithm dermatology pruritus secondary generalized oncology systemic arteritis biliary cholangitis cirrhosis ckd gap gca globulin hemodialysis hepatology infections infectiousdiseases leukemia
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
Differential Diagnosis ... Reactive: • Anemia ... Polycythemia Vera • Primary ... Diagnosis #causes ... #Platelets #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... malignancies • Anemia ... Post-splenectomy Primary ... MF) • Chronic myeloid ... Diagnosis #Causes
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... - Differential ... Myelogenous Leukemia • Primary ... Iron deficiency anemia ... #Causes #Hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Diagnosis Algorithm ... Causes == Primary ... renal failure/uremia ... Diagnosis #Algorithm ... #causes
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... purple, hemorrhagic skin ... /Quantity: • Primary ... - Hemolytic anemia ... #Diagnosis #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
- infiltrates (anemia ... + distinctive primary ... CLL -> Invade Skin ... #Leukemia #Hematology ... #Oncology #Diagnosis
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... Examination: • Skin ... bile ducts Differential ... #workup #hepatology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic complaints- anemia ... , thrombocytosis ... required due to skip ... #GiantCell #arteritis ... #Management
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Pruritus - No Primary ... Skin Lesion - Differential ... Diagnosis Algorithm ... renal failure/uremia ... #causes
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... , or all three myeloid ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
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