6 results
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Diagnosis Algorithm ... Agglutination - Cold ... thrombocytopenia - DIC, TTP, HELLP ... #Diagnosis #Algorithm ... #workup #hematology
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Differential Diagnosis ... disease • Hypersplenism ... • AIHA: warm, cold ... TTP, HUS, DIC, HELLP ... classification #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral Infection Clinical ... Diagnosis: • hemolytic ... younger pts) Differential ... significance (MGUS), CLL, Myeloma ... #hematology #diagnosis
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Liver Disease in ... #hepatology #obstetrics ... hepatitis #comparison #differential ... #diagnosis #icp ... #HELLP #AFLP
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Diagnosis Algorithm ... lymphoma, melanoma, myeloma ... • Pregnancy: HELLP ... #diagnosis #algorithm ... #hepatology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Coombs (-) hemolytic ... anemia due to cold ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology