7 results
Upper Motor Neuron (UMN) lesions are lesions occurring anywhere in the CNS from the brain up
may arise from disease ... its surrounding myelin ... pathology and muscle disorders ... disorder and form ... LMN syndromes are
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
multiple spinal cord ... and LMN signs in ... and LMN signs to ... and LMN signs on ... EMG: LMN Signs in
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Non-neuromuscular disorder ... of the spinal cord ... Inflammatory: Myeloma ... Gravis - Lack of UMN ... /LMN signs - Lack
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Spinal Cord Disorders ... • Symptoms and signs ... Sarcoidosis, Behcet disease ... MCTD, Sjogren syndrome ... : Areflexia UMN
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
extensors of the arms (pyramidal ... • Bilateral signs ... vaccination - Myelin ... Myelitis #diagnosis #management ... #neurology #differential
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
neurodegenerative disease ... • Or brainstem syndromes ... Examination: • UMN ... impairment, Mood disorder ... Progressive MS (Spinal cord
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Diagnosis and Management ... brain and spinal cord ... other neurological disorders ... limb or joint disorders ... SPS #Diagnosis #Management