30 results
Parinaud's Syndrome
What?
 - Impaired upgaze
 - Light-near dissociation
 - Convergence retraction nystagmus
 - Eyelid retraction (Collier's
Parinaud's Syndrome ... retraction nystagmus - Eyelid ... → "setting sun sign ... " - Vascular disease ... diagnosis #pineal #neurology
Parinaud's syndrome
What?
 • Light-near dissociation (tectal pupils)
 • Convergence retraction nystagmus
 • Eyelid retraction (Collier's sign)
Parinaud's syndrome ... retraction nystagmus • Eyelid ... "setting sun" sign ... • Vascular disease ... #neurology #diagnosis
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
mutations - Down syndrome ... chromosome 21) Signs ... pathophysiology #geriatrics ... #diagnosis #signs ... #symptoms
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
less systemic symptoms ... , holster sign, ... anti-synthetase syndrome ... after 2 years of treatment ... Myositis #diagnosis #rheumatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... changes, stroke symptoms ... WBC >100k, + lab signs ... organ damage • Treatment ... diagnosis #management #hematology
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Anterior Cord Syndrome ... injury, often from vascular ... pathophysiology #signs ... #symptoms #msk ... #orthopedics #neurology
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Inflammatory: Myeloma ... Lack of UMN/LMN signs ... myositis • Genetic: Muscular ... myopathies, the muscular ... Differential #Diagnosis #neurology
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Signs and symptoms ... Multiple Sclerosis Treatment ... diagnosis #management #neurology ... #treatment #MS
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
meningitis), MCC CNS symptoms ... and diplopia) • Vascular ... Arthritis, AS Treatment ... diagnosis #management #signs ... #symptoms #rheumatology
Rheumatoid Arthritis - Signs and Symptoms
 • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans
 • Pulmonary:
Rheumatoid Arthritis - Signs ... and Symptoms • ... nephritis, AA amyloid ... Thrombocytosis, Felty's syndrome ... #rheumatology