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diagnosis oncology agglutinin aki cold erythematosus gap globulin hemolytic injury kidney lupus nephrology paraproteinemias proteingap rheumatology significance sle systemic undetermined
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
Monoclonal Gammopathy ... cancer for which ... No evidence of anemia ... insufficiency, Anemia ... #Monoclonal #Gammopathy
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
tubulopathy • Monoclonal ... gammopathy of renal ... • Hematologic ... #Oncology #Differential ... #Diagnosis #Classification
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
: • MGUS • Multiple ... myeloma • Waldenstrom ... ovarian tumors, lung cancers ... Thalassemia, Sickle cell anemia ... Gap #ProteinGap #differential
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Protein/M Component ... • Heavy Chain disease ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... #Monoclonal #Differential
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
younger pts) Differential ... gammopathy of undetermined ... significance (MGUS ... ), CLL, Myeloma ... #hematology #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: ... • Acute cutaneous ... permanent alopecia Differential ... pancreatitis, protein-losing ... lymphopenia, low PLT • Anemia
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