39 results
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
vasculitis • Hematologic ... criteria for 1) hematologic ... (12%) • giant cell ... hematopoietic stem cells ... cells NEJM Review
Plasmacytomas and Plasma-Cell Leukemia - Physical examination revealed multiple exophytic subcutaneous lesions involving the arms and
Plasmacytomas and Plasma-Cell ... involving the arms ... shows the right arm ... Clinical #HONC #Derm ... Leukemia #Smear #NEJM
Hypersegmented neutrophil in a case of acute myeloid leukemia.

Dysplastic neutrophils are typically hypolobated but can be
case of acute myeloid ... Dysplastic neutrophils are ... AML #Clinical #Hematology ... #Pathology #Smear
Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
Plasma cell leukemia ... other forms of myeloma ... primary plasma cell ... Clinical #Smear #Hematology ... #Pathology
Dysmorphic Red Blood Cells on Electron Microscopy
This eyeSCANdy image shows dysmorphic red blood cells from the
Dysmorphic Red Blood Cells ... dysmorphic red blood cells ... SEM #clinical #pathology ... #hematology #nephrology
Excoriated papules with honey-colored crusting were present on the abdomen, back (Panel A), arms, and legs.
back (Panel A), arms ... #Clinical #Derm ... #Pathology #Scabies ... Microscopy #Rash #NEJM
Prolymphocytes

In our case, the patient has T-prolymphocytic leukemia (T-PLL) not Acute Myeloid Leukemia (AML).  🔬Tumor
T-PLL) not Acute Myeloid ... 🔬Tumor cells are ... size lymphoid cells ... Smear #Peripheral #Pathology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
CML (Chronic Myeloid ... • Neutrophils (myeloid ... AML (Acute Myeloid ... are in the Lymph ... #Leukemia #Hematology
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
total white blood cell ... similarly to mast cells ... granules which are ... Disorders: • Chronic myeloid ... Diagnosis #causes #hematology
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
non-specific red cell ... polychromatophilic cells ... smear changes are ... hemolytic #anemia #Hematology ... #Pathology #Smear