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VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
thromboembolic disease ... vasculitis • Hematologic ... criteria for 1) hematologic ... cells NEJM Review ... Autoinflammatory #Somatic #rheumatology
Dysplasia in Myelodysplastic Syndrome - Dysgranulopoiesis - Dyserythropoiesis - Dysmegakaryopoiesis #Dysplasias #MDS #Myelodysplastic
Myelodysplastic Syndrome ... Myelodysplastic #Syndrome ... #Pathology #Hematology
Hypersegmented neutrophil in a case of acute myeloid leukemia. Dysplastic neutrophils are typically hypolobated but can be
case of acute myeloid ... AML #Clinical #Hematology ... #Pathology #Smear
Pathologic Red Blood Cell (RBC) Morphologies and Associated Diseases Acanthocyte (spur cell), Basophilic stippling, Bite cell,
Pathologic Red Blood ... and Associated Diseases ... Atlas #Microscopy #Pathology ... #Hematology #Diagnosis ... Basis of Disease
Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
Aggressive disease ... other forms of myeloma ... Clinical #Smear #Hematology ... #Pathology
Raynaud's Phenomenon on Physical Exam #Raynauds #Syndrome #disease #phenomenon #clinical #video #physicalexam #fingers #hands #rheumatology
#Raynauds #Syndrome ... #disease #phenomenon ... fingers #hands #rheumatology
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 A non-subtle example of true Sezary syndrome. Patient presented with erythroderma without antecedent history of
of true Sezary syndrome ... mjcascio #Sezary #Syndrome ... Cells #Clinical #Pathology ... Smear #Microscopy #Hematology
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
Churg-Strauss syndrome ... - Goodpasture syndrome ... - Schnitzler syndrome ... - Sjögren syndrome ... Vessels #Diagnosis #Rheumatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... • Nonmalignant hematologic ... Vasculitides, IBD, Celiac disease ... Kawasaki, Nephrotic syndrome ... Diagnosis #Algorithm #hematology
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... lymphoma, multiple myeloma ... thrombocythemia), Autoimmune disease ... vonWillebrand #Syndrome ... Management #treatment #hematology
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