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diagnosis differential management signs vasculitis lupus oncology sle erythematosus leukemia rheumatoid workup arteritis autoimmune autoinflammatory behcet cll common comparison cryofibrinogenemia
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
Classification of ... central nervous system ... - systemic ... induced by chronic ... Vessels #Diagnosis #Rheumatology
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
thromboembolic disease ... Abnormalities: macrocytic anemia ... • giant cell arteritis ... cells NEJM Review ... Autoinflammatory #Somatic #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
of hip (rare), Arthritis ... Demyelinating syndromes ... pain (20%) Renal disease ... ) Blood (75%): Anemia ... #diagnosis #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... meningitis), MCC CNS symptoms ... Recurrent and chronic ... management #signs #symptoms ... #rheumatology #
Rheumatoid Arthritis - Signs and Symptoms • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans • Pulmonary:
Rheumatoid Arthritis ... - Signs and Symptoms ... Hematological: Anemia ... Thrombocytosis, Felty's syndrome ... #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: ... lymphopenia, low PLT • Anemia ... Induced Lupus: • Symptoms ... with Lupus: • Chronic ... Erythematosus #Diagnosis #Rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... -> AML: Blast crises ... - infiltrates (anemia ... • Tumor lysis syndrome ... #Leukemia #Hematology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
complaints- anemia ... in literature (NEJM ... (Cornelia NEJM ... them, but urgent rheumatology ... Temporal #Signs #Symptoms
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Eosinophilia, asthma, chronic ... tract, and often causes ... Symptoms (Sx) in ... differential #diagnosis #rheumatology ... #classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... • Autoimmune diseases ... diagnosis #types #classification ... #rheumatology #
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