20 results
 End Stage Liver Disease (Cirrhosis) - Complications 
 • Ascites
 • Esophageal Varices
 • Hepatic
Disease (Cirrhosis ... Complications • Ascites ... Hepatopulmonary Syndrome ... • Hepatorenal Syndrom ... management #summary #hepatology
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
thromboembolic disease ... vasculitis • Hematologic ... criteria for 1) hematologic ... peripheral blood myeloid ... cells NEJM Review
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
- Budd-Chiari syndrome ... Liver disease ... - Acute fatty liver ... - Nephrotic syndrome ... #differential #hepatology
Ascites - Differential Diagnosis
Chronic liver disease (cirrhosis or chronic hepatitis) - 80%
Underlying malignancy - 10%
Congestive heart
Ascites - Differential ... Diagnosis Chronic liver ... disease (cirrhosis ... Fitz-Hugh-Curtis syndrome ... Chylous <1% #Ascites
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
of portal HTN: ascites ... and hepatorenal syndrome ... portal HTN: • Ascites ... • Budd Chiari syndrome ... sarcoidosis) • Liver
Causes of Ascites - Differential Diagnosis Algorithm
Portal Hypertension - Prehepatic:
 • Portal vein thrombosis
 • Splenic
Causes of Ascites ... • Infiltrative disease ... • Acute liver ... • Budd-Chiari syndrome ... Diagnosis #Algorithm #Hepatology
Elevated Transaminases / Transaminitis - Differential Diagnosis

 • Infectious: HAV, HCV, HEV, EBV, HSV, CMV
 •
lymphoma, melanoma, myeloma ... Trauma: Shock liver ... Metabolic: Wilson Disease ... Vascular: Budd-chiari syndrome ... Diagnosis #causes #hepatology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
• Pancreatic Disease ... Formation • Multiple Myeloma ... Myelodysplastic Syndromes ... Disease #Macrocytic ... Algorithm #Causes #Hematology
Hepatomegaly - Differential Diagnosis Algorithm
Malignant
 • Primary Carcinoma
 • Metastases
 • Lymphoma
 • Leukemia
 • Polycythemia
Polycythemia • Multiple Myeloma ... Non-Malignant • Fatty Liver ... Hemochromatosis • Wilson's Disease ... • Budd-Chiari Syndrome ... Algorithm #Causes #Hepatology
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis
High albumin gradient (>1.1 g/dl):
 - Cirrhosis	
 - Alcoholic
- Massive liver ... thrombosis (Budd-Chiari syndrome ... Veno-occlusive disease ... - Acute fatty liver ... connective tissue disease