10 results
This image shows portions of glomerular tuft with collapsed GBM (across top), spicular amyloid (middle right),
top), spicular amyloid ... amyloid (middle ... glomerulus #GBM #amyloid ... ElectronMicroscopy #SEM ... clinical #nephrology #pathology
This image shows spicular amyloid with tapering conical masses interconnected by branching fibrils!

Dr. Stephen Bonsib via
shows spicular amyloid ... arkanalabs #amyloid ... ElectronMicroscopy #SEM ... clinical #nephrology #pathology
This image shows spicular amyloid deposits showing blunt conical formations with interconnecting fibrils.

Dr. Stephen Bonsib via
shows spicular amyloid ... arkanalabs #amyloid ... ElectronMicroscopy #SEM ... clinical #nephrology #pathology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Myasthenia Gravis ... Overview Myasthenia ... Ocular- 50%: Ptosis ... dystrophy - Brain stem ... /Cranial nerve pathology
This image shows glomerular tuft with overall intact architecture. Discrete masses of specular amyloid interrupt smooth
masses of specular amyloid ... CapillaryLoop #glomerulus #amyloid ... ElectronMicroscopy #SEM ... clinical #nephrology #pathology
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
thrombocytopenia, multiple myeloma ... conditions - multiple myeloma ... hematopoietic stem ... peripheral blood myeloid ... cells NEJM Review
This image shows a glomerular tuft with overall intact architecture. Discrete masses of specular amyloid (long
masses of specular amyloid ... #glomerulus #amyloid ... ElectronMicroscopy #SEM ... clinical #nephrology #pathology
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Inflammatory: Myeloma ... /amyloid • Infectious ... Postsynaptic: Myasthenia ... anti-La/SSB, anti-Sm
Summary of characteristic abnormalities of selected glomerular diseases
Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
Electron Microscopy (EM ... Membranous GN • Amyloid ... diseases #nephrology #pathology
Perirenal Extramedullary Hematopoiesis - Magnetic resonance imaging of the abdomen, performed without the administration of contrast
erythroid and myeloid ... cilnical #Radiology #Pathology ... ExtramedullaryHematopoiesis #Microscopy #NEJM