15 results
Cholestatic Liver Disease: Primary Biliary Cirrhosis vs Primary Sclerosing Cholangitis

#pathophysiology #pbc #psc #hepatology #comparison
Liver Disease: Primary ... Biliary Cirrhosis ... vs Primary Sclerosing ... Cholangitis #pathophysiology ... #pbc #psc #hepatology
Primary Biliary Cirrhosis - Pathophysiology
Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish
Epigentics Risk
Primary Biliary ... Cirrhosis - Pathophysiology ... Cholestasis #PBC #Primary ... #Biliary #Cirrhosis ... #hepatology
Hepatomegaly - Differential Diagnosis Algorithm
Malignant
 • Primary Carcinoma
 • Metastases
 • Lymphoma
 • Leukemia
 • Polycythemia
Malignant • Primary ... Polycythemia • Multiple Myeloma ... Cholangitis • Primary ... Biliary Cirrhosis ... Algorithm #Causes #Hepatology
Systemic Sclerosis Associated Autoantibodies
Anti-topoisomerase I (anti-Sc170): Diffuse skin disease, Pulmonary fibrosis
Anti-centromere: Limited skin disease (~93-95%), Pulmonary
anti-Sc170): Diffuse skin ... Digital ulcers, Primary ... Biliary Cirrhosis ... Rapid progressive skin ... Autoantibodies #diagnosis #rheumatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary ... 65 years PBC Pathophysiology ... Examination: • Skin ... #Biliary #Cirrhosis ... diagnosis #workup #hepatology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
hypersplenism and related thrombocytopenia ... Clues to non-cirrhotic ... pregnancy • Primary ... biliary cirrhosis ... Diagnosis #causes #hepatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... /Quantity: • Primary ... Causes: - Thrombocytopenia ... Differential #Diagnosis #hematology ... #rheumatology #
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Heparin Induced Thrombocytopenia ... arterial thrombosis, skin ... ♀, ↑Age, ESRD Pathophysiology ... exposure (prevent skin ... Management #Treatment #Hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
transfusion • Thrombocytopenia ... protein C and S Pathophysiology ... coagulopathy - Thrombocytopenia ... Treatment: • Treat primary ... treatment #management #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
CML (Chronic Myeloid ... infiltrates (anemia, thrombocytopenia ... + distinctive primary ... CLL -> Invade Skin ... #Leukemia #Hematology