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Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
rapid onset of weakness ... the spinal cord (Myelopathy ... Weakness: - Weakness ... distribution of weakness ... Myelitis #diagnosis #management
Neurological Patterns of Weakness • Hemispheric lesion • Brainstem lesion • Spinal cord lesion • Polyneuropathy
Neurological Patterns of Weakness ... Polyneuropathy • Myopathy ... Neurology #Patterns #Weakness
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
symmetric muscle weakness ... symmetric muscle weakness ... Fever, No muscle weakness ... asymmetric muscle weakness ... Proximal muscle weakness
Myositis and Myopathies #ESR #CK #Differential diagnosis of myopathy #Inflammatory #myopathies #Dermatomyositis #muscle weakness #Polymyositis #Inclusion body myositis #Polymyalgia rheumatica #Fibromyalgia #Hypothyroid myopathy #Muscle stiffness #Drug-induced
Differential diagnosis of myopathy ... Dermatomyositis #muscle weakness ... #Hypothyroid myopathy ... Statin-induced myopathy ... Cocaine-induced myopathy
Myelopathy - Injury to the entire spinal cord - Signs and Symptoms • Ataxia (early sign)
Myelopathy - Injury ... • Gross motor weakness ... early signs) #Myelopathy
Creatine Kinase - Causes of Elevated CK Levels Acute CK Elevation (Pain > Weakness): • RHABDOMYOLYSIS
Elevation (Pain > Weakness ... Critical Illness Myopathy ... Chronic Causes (Weakness ... PROXIMAL MUSCLE WEAKNESS ... - Inflammatory myopathy
Causes of Proximal Muscle Weakness That May Mimic Inflammatory Myopathy • Central or peripheral neurologic disease
Proximal Muscle Weakness ... Mimic Inflammatory Myopathy ... Mitochondrial myopathy ... MuscleWeakness #Myopathy
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
proximal myalgia and weakness ... symmetric muscle weakness ... • Inflammatory myopathy ... Statin-induced myopathy ... #diagnosis #management
Causes of Peripheral Weakness - With and Without Sensory Changes - Differential Diagnosis Algorithm With Sensory Changes:
of Peripheral Weakness ... • No Objective Weakness ... Oculomotor • Myopathy ... #Peripheral #Weakness
Hypothyroidism – symptoms and signs. Symptoms: Tiredness/malaise, Weight gain, Anorexia, Cold intolerance, Poor memory, Change in appearance, Depression, Poor libido,
Myalgia, Muscle weakness ... Psychosis, Deafness ... of movement, Deafness ... hypertrophy, Proximal myopathy
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