30 results
Idiopathic Thrombocytopenic Purpura 
Clinical:
 • Gingival 
 • Menorrhagia 
 • GI bleeding 
 • Intracranial
Idiopathic Thrombocytopenic ... children) • Platelets ... extremely low platelet ... #Purpura #Thrombocytopenia ... Diagnosis #Overview #Hematology
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
receptor] • Thrombocytopenia ... , Large platelets ... chain IIA • Thrombocytopenia ... fibrinogen) • Thrombocytopenia ... differential #diagnosis #hematology
Causes of Thrombocytopenia.
Platelet counts may be depressed because of decreased production or due to increased platelet
Causes of Thrombocytopenia ... Platelet counts ... due to increased platelet ... #Diagnosis #Hematology ... #Thrombocytopenia
Approach to suspected Heparin-Induced Thrombocytopenia (HIT)

 • Suspected HIT Algorithm
 • "4 T's" clinical probability score:
Heparin-Induced Thrombocytopenia ... score: - Thrombocytopenia ... (platelet count ... Timing of onset of platelet ... #HIT #hematology
Algorithm for diagnosis of familial thrombocytopenia. Platelet size, best determined by review of the peripheral smear,
diagnosis of familial thrombocytopenia ... Platelet size, best ... #Diagnosis #Hematology ... #Familial #Thrombocytopenia
4-T Score for the Likelihood of Heparin Induced Thrombocytopenia
 - Thrombocytopenia - Compare the highest platelet
count
Heparin Induced Thrombocytopenia ... - Thrombocytopenia ... Compare the highest platelet ... - Timing (of platelet ... Likelihood #Diagnosis #Hematology
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
Platelet disorders ... count and platelet ... Gplb receptor • Thrombcytopenia ... • Platelet flow ... #disorders #hematology
Thrombocytopenia - Differential Diagnosis Algorithm

Decreased production:
 • Bone marrow suppression
 • Bone marrow failure
 • Bone
Thrombocytopenia ... MatthewHoMD #Thrombocytopenia ... Diagnosis #Algorithm #hematology ... #platelets
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Diagnosis Algorithm Thrombocytopenia ... Sequestration Disordered Platelet ... - Acquired • Anticoagulation ... Algorithm #Causes #Hematology
4T Score for Heparin-Induced Thrombocytopenia

Interpretation of the 4T score:
0-3 points:  Low probability (<<1%)
  -
Heparin-Induced Thrombocytopenia ... Consider therapeutic anticoagulation ... Initiate therapeutic anticoagulation ... HeparinInduced #Thrombocytopenia ... Diagnosis #Criteria #Hematology