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diagnosis rhabdomyolysis causes differential management nephrology algorithm ck lfts liver tests treatment workup acute acutemyocardialinfarction aki alkaline alkpos alt ami
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism AST and ALT: • AST: liver
(80% Hgb, rest myoglobin ... Metabolism #ASTALT #AlkPhos
Features of Components of Liver Function Tests #Diagnosis #IM #GI #LFTs #Liver #Function #Tests #Locations #AlkPhos
Tests #Locations #AlkPhos
Algorithm for evaluation of elevated serum alkaline phosphatase. #Algorithm #elevated #alkaline #phosphatase #AlkPhos #Elevation #Diagnosis #workup
#phosphatase #AlkPhos
RHABDOMYOLYSIS • Characterized by skeletal muscle breakdown & necrosis. • Elevated Creatine kinase (CK) hallmark of rhabdomyolysis. • Defined based
• Myoglobin half-life ... metabolism makes myoglobin
Creatine kinase (CK) is an intracellular enzyme present in skeletal muscle, myocardium & brain; smaller amounts
Myoglobin levels ... Myoglobin has a ... metabolism makes serum myoglobin ... creatinekinase #CK #myoglobin
HAS-BLED Score - Hypertension: Baseline SBP > 160mmHg - Renal disease: Cr > 2.6mg/dL, on HD,
ULN, or AST/ALT/alkphos
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Rhabdo-myolysis: CK, myoglobin
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
with no RBC’s, + myoglobin ... Direct myoglobin
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
Direct myoglobin
Anaplastic large cell lymphoma, ALK+ Clinical • First 3 decades of life, M>F • Often nodal +
largecell #lymphoma #ALKPos
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