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Idiopathic Inflammatory Myopathies - Dermatomyositis (DM), Immune-Mediated Necrotizing Myopathy (IMNM), Antisynthetase Syndrome (ASS), Inclusion Body Myositis
Idiopathic Inflammatory ... Myopathies - ... TerrierBen #Inflammatory ... #Myopathy #Comparison ... #Managment #algorithm
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
Myoglobinuria DDX: • Inflammatory ... , toxic myopathy ... Statins → Inflammatory ... : Inflammatory statin ... #diagnosis #management
Myositis and Myopathies #ESR #CK #Differential diagnosis of myopathy #Inflammatory #myopathies #Dermatomyositis #muscle weakness #Polymyositis #Inclusion body myositis #Polymyalgia rheumatica #Fibromyalgia #Hypothyroid myopathy #Muscle stiffness #Drug-induced
Myositis and Myopathies ... #Inflammatory ... #myopathies #Dermatomyositis ... #Hypothyroid myopathy ... Statin-induced myopathy
Causes of Proximal Muscle Weakness That May Mimic Inflammatory Myopathy • Central or peripheral neurologic disease
That May Mimic Inflammatory ... Myopathy • Central ... • Metabolic myopathies ... Mitochondrial myopathy ... MuscleWeakness #Myopathy
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
Myositis and Myopathies ... load Drug-induced myopathy ... Gemcitabine Lupus Myopathy ... 5-15% of lupus myopathy ... #myopathy #differential
Creatine Kinase - Causes of Elevated CK Levels Acute CK Elevation (Pain > Weakness): • RHABDOMYOLYSIS
Critical Illness Myopathy ... - Metabolic Myopathies ... toxoplasmosis - Inflammatory ... myopathy: dermatomyositis ... polymyositis, necrotizing myopathy
Idiopathic Inflammatory Myopathies (IIM's) RASH + MUSCLE WEAKNESS → Consider idiopathic inflammatory myopathies (IIM's) • Overlap Myositis
Idiopathic Inflammatory ... Myopathies (IIM's ... myopathies (IIM's ... myopathy that occurs ... myopathy affecting
Seronegative Inflammatory Arthritis - Differential Diagnosis • Seronegative Rheumatoid Arthritis • Infectious Arthritis: Viral, Bacterial,
Seronegative Inflammatory ... Still's Disease, Inflammatory ... Myopathy • Crystal ... #Seronegative #Inflammatory
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
spinal cord • Inflammatory ... Paraneoplastic syndrome • Inflammatory ... proximal weakness Myopathy ... : • Inflammatory ... • Metabolic myopathies
Inflammatory Myopathies Dermatomyositis • Onset: Subacute • Pattern: Proximal • CK: Up to 50X ULN • Autoantibodies:
Inflammatory Myopathies ... BrighamChiefs #Inflammatory ... #Myopathies #differential
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