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diagnosis differential rheumatology causes clinical neurology management signs symptoms systemic algorithm msk erythematosus lupus muscle myopathy pocus sle treatment syndrome
Myositis and Myopathies #ESR #CK #Differential diagnosis of myopathy #Inflammatory #myopathies #Dermatomyositis #muscle weakness #Polymyositis #Inclusion body myositis #Polymyalgia rheumatica #Fibromyalgia #Hypothyroid myopathy #Muscle stiffness #Drug-induced
Myositis and Myopathies ... #Inflammatory #myopathies ... Inclusion body myositis ... #Drug-induced myopathies
Idiopathic Inflammatory Myopathies - Dermatomyositis (DM), Immune-Mediated Necrotizing Myopathy (IMNM), Antisynthetase Syndrome (ASS), Inclusion Body Myositis
Idiopathic Inflammatory Myopathies ... Inclusion Body Myositis ... #Inflammatory #Myopathies
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
Myositis and Myopathies ... Inclusion Body Myositis ... , +Anti-dsDNA, Myositis ... BostonChiefs #Myositis ... #Myopathies #myopathy
Idiopathic Inflammatory Myopathies (IIM's) RASH + MUSCLE WEAKNESS → Consider idiopathic inflammatory myopathies (IIM's) • Overlap Myositis
Idiopathic Inflammatory Myopathies ... idiopathic inflammatory myopathies ... • Overlap Myositis ... Inclusion body myositis ... #Inflammatory #Myopathies
Inflammatory Myopathies Dermatomyositis • Onset: Subacute • Pattern: Proximal • CK: Up to 50X ULN • Autoantibodies:
Inflammatory Myopathies ... Necrotizing Autoimmune Myositis ... Inclusion Body Myositis ... #Inflammatory #Myopathies
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Inclusion body myositis ... • Metabolic myopathies ... anti-RNP - (Myositis ... inclusion body myositis ... certain drug-induced myopathies
Creatine Kinase - Causes of Elevated CK Levels Acute CK Elevation (Pain > Weakness): • RHABDOMYOLYSIS
- Metabolic Myopathies ... Inclusion body myositis
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
• Myalgia • Myositis ... inclusion body myositis ... → Inflammatory myopathies
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis ... Inflammatory Myopathies ... , drug-induced myopathies ... INCLUSION BODY MYOSITIS ... lung disease • Myositis
Acute Myelopathies. #AcuteMyelopathies #Myelopathy #schema
Acute Myelopathies
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