73 results
diagnosis differential neurology clinical rheumatology signs symptoms causes algorithm endocrinology physicalexam weakness pathophysiology pocus syndrome video dermatomyositis hypothyroid inflammatory lupus
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
• Inflammatory myopathy ... hypothyroid-induced myopathy ... Statin-induced myopathy ... - Necrotizing myopathy ... fibers Risk of myopathy
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
rimmed vacuoles HIV myopathy ... load Drug-induced myopathy ... Gemcitabine Lupus Myopathy ... 5-15% of lupus myopathy ... Myositis #Myopathies #myopathy
Causes of Proximal Muscle Weakness That May Mimic Inflammatory Myopathy • Central or peripheral neurologic disease
Mimic Inflammatory Myopathy ... Mitochondrial myopathy ... MuscleWeakness #Myopathy
Idiopathic Inflammatory Myopathies - Dermatomyositis (DM), Immune-Mediated Necrotizing Myopathy (IMNM), Antisynthetase Syndrome (ASS), Inclusion Body Myositis
Immune-Mediated Necrotizing Myopathy ... Myopathies #Idiopathic #Myopathy
Hypothyroid Myopathy Very common (up to 80% ) in patients with hypothyroidism Pathophysiology: • T4 deficiency leads to
Hypothyroid Myopathy ... Symmetric, proximal myopathy ... #Hypothyroid #Myopathy
Bilateral Foot Drop secondary to Nonaka Myopathy 48 yr old lady, difficulty in climbing stairs x 8
secondary to Nonaka Myopathy ... recessive Nonaka myopathy ... GNE myopathy, also ... as HIBM, Nonaka myopathy ... IBM2 and distal myopathy
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 Idiopathic Inflammatory Myopathies (IIM's) RASH + MUSCLE WEAKNESS → Consider idiopathic inflammatory myopathies (IIM's) • Overlap Myositis
Any inflammatory myopathy ... Inflammatory myopathy ... #dermatology #Myopathy
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
NECROTIZING AUTOIMMUNE MYOPATHY ... syndrome • If myopathy ... ANTI-MITOCHONDRIAL MYOPATHY ... Autoimmune #Myositis #Myopathy
Myositis and Myopathies #ESR #CK #Differential diagnosis of myopathy #Inflammatory #myopathies #Dermatomyositis #muscle weakness #Polymyositis #Inclusion body myositis #Polymyalgia rheumatica #Fibromyalgia #Hypothyroid myopathy #Muscle stiffness #Drug-induced
Differential diagnosis of myopathy ... #Hypothyroid myopathy ... Corticosteroid-induced myopathy ... Statin-induced myopathy ... Cocaine-induced myopathy
Neurological Patterns of Weakness • Hemispheric lesion • Brainstem lesion • Spinal cord lesion • Polyneuropathy
Polyneuropathy • Myopathy
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