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diagnosis management anca antibody antineutrophil antinxp2 antinxp2dm dermatomyositis differential disease diseases erythematosus hematology igg4 lupus monoclonal oncology paraproteinemias phenotypes related
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... scleroderma) - Anti-Scl ... Jcortesizaguirr #ANA ... #Antinuclear #Antibody ... #rheumatology #
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
aorta • Head and ... pancreas, biliary, renal ... serum lgE, no autoantibodies ... (antinuclear antibodies ... workup #treatment #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
(HCV) • CLL & MBL ... macular Vasculitis) Autoantibodies ... vascular beds-renal ... , retinal, DVT, ... Paraproteinemias #Hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
• Anti-Ro/SSA autoantibodies ... Non-autoimmune rheumatologic ... La, anti-Jo-1, SCL ... -70, RNP antibodies ... anticardiolipin antibodies
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
without these autoantibodies ... • Antibodies targeting ... • Clear cell renal ... diagnosis #management #rheumatology ... #dermatology
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