18 results
Myotonic Dystrophy
Typically presents in middle age with weakness of hands, legs and neck.
 - Mental deficiency
Myotonic Dystrophy ... - Myotonia occurs ... #Myotonic #Dystrophy ... #Myotonia #Diagnosis ... #signs #symptoms
Hypothyroidism – symptoms and signs.

Symptoms: 
Tiredness/malaise, 
Weight gain,
Anorexia,
Cold intolerance, 
Poor memory,
Change in appearance, 
Depression, 
Poor libido,
– symptoms and signs ... , Deafness Signs ... Carpal timel syndrome ... Mild obesity, Myotonia ... Hypothyroid #Features #Signs
Causes of Hypotonic Infant (Floppy Newborn) - Differential Diagnosis Algorithm
Central Nervous System - Decreased LOC, Axial
Causes of Hypotonic ... Infant (Floppy Newborn ... Other Congenital Syndromes ... • Congenital Myotonic ... Infant #Floppy #Newborn
Causes of Pediatric Constipation - Differential Diagnosis Algorithm
Dietary / Functional:
 • Insufficient Volume / Bulk
Neurologic:
 •
Cord Lesions • Myotonia ... Guillain-Barré Syndrome
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Guillain-Barre syndrome ... Lambert Eaton Syndrome ... Muscular dystrophy, Myotonic
Scarf Sign (Normal) on Physical Exam

The scarf sign is used to assess developmental age and muscle
Scarf Sign (Normal ... Exam The scarf sign ... chest; in the hypotonic ... clinical #video #hypotonia ... #hypotonic #peds
Ptosis - Differential Diagnosis Framework

Ptosis (Greek- to fall) Drooping of the upper eyelid that usually results
Horner’s syndrome ... palsy • Horner syndrome ... Ophthalmoplegia migraine Myogenic ... Mitochondrial myopathy • Myotonic ... Blepharophimosis syndrome
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
thyroid, Sjogren syndrome ... “dropping head syndrome ... - Myotonic dystrophy ... test - Cogan sign ... - Peek sign
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
mutations - Down syndrome ... chromosome 21) Signs ... Motor dysfunction: myoclonic ... geriatrics #diagnosis #signs
Characteristic clinical manifestations of Down syndrome 
 
Typical craniofacial appearance 
 • Round face and flat
manifestations of Down syndrome ... between toes • Hypotonia ... #Downs #Syndrome ... PhysicalExam #Features #Signs