113 results
Hypercalcemia of Malignancy - Pathophysiology
PTH-mediated
 • Parathyroid cancer
 • Ectopic production: Small cell lung cancer, ovarian
of Malignancy - Pathophysiology ... resorption in the bone ... resorption in the bone ... Hypercalcemia #Malignancy #Pathophysiology ... #Differential #
Stress Fracture: Pathogenesis and clinical findings
Abnormal biomechanics, Repetitive impact activities
=> Repetitive subthreshold mechanical loading
=> Bone strain
=>
Pathogenesis and clinical ... mechanical loading => Bone ... strain => Bone ... #orthopedics #pathophysiology
Pisa Syndrome (pleurothotonus) on Physical Exam
A tonic flexion of the trunk of the body to one
of the body to one ... degrees due to dystonia ... Pathophysiology: ... #PhysicalExam #clinical
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
heavy metals), Critical ... Muscular dystrophy, Myotonic ... Weakness #Causes #differential
Scarf Sign (Normal) on Physical Exam

The scarf sign is used to assess developmental age and muscle
age and muscle tone ... infant with normal tone ... #PhysicalExam #clinical ... #video #hypotonia ... peds #pediatrics #tone
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... Neuropathy ALP is critical ... : Inhibitor of bone ... collection with EDTA Pathophysiology ... Muscular/Rheum: - Hypotonia
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings
 • Subtrochanteric region spans 5 cm distally from the
Pathogenesis and clinical ... Bisphosphonate suppresses bone ... damage weakens the bone ... orthopedics #diagnosis #differential ... #causes #pathophysiology
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Gaucher Disease Pathophsiology ... in GBA1 gene Clinical ... Osteonecrosis, bone
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Pathogenesis and clinical ... Sporadic mutation -> One ... gene mutated in one ... Inherited mutation -> One ... Retinoblastoma #pathophysiology
Purple Urine Bag Syndrome
Chronic, indwelling catheter + bacteriuria (Providencia, Klebsiella, E.coli*) + alkaline urine
Tryptophan → Indoxyl
Syndrome #PUBS #pathophysiology ... #clinical #photo ... #differential #