26 results
Elevated Transaminases / Transaminitis - Differential Diagnosis

 • Infectious: HAV, HCV, HEV, EBV, HSV, CMV
 •
breast CA, small cell ... lymphoma, melanoma, myeloma ... Vascular: Budd-chiari syndrome ... Sinusoidal obstruction syndrome ... Diagnosis #causes #hepatology
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
Chronic Hepatitis ... treat the pts with chronic ... viremia or have cirrhosis ... Diagnosis #Management #Treatment ... #Hepatology
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... Family history of cirrhosis ... or fibrosis • Cirrhosis ... ) • Use of B-cell ... #management #hepatology
Ascites - Differential Diagnosis
Chronic liver disease (cirrhosis or chronic hepatitis) - 80%
Underlying malignancy - 10%
Congestive heart
liver disease (cirrhosis ... or chronic hepatitis ... Fitz-Hugh-Curtis syndrome ... ), HIV-related, ... Differential #Diagnosis #hepatology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... microglobulin Treatment ... #Chronic #Lymphocytic ... diagnosis #workup #oncology ... #hematology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... in those with CLD ... (± cirrhosis) w ... months without treatment ... #Hepatology #gastroenterology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... Allogeneic stem cell ... only curative treatment ... Myelodysplastic #Syndrome ... #hematology #oncology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
vein: Budd-chiari syndrome ... > 2 • NASH, Chronic ... hepatitis: < 1 • Cirrhosis ... injury: > 3 • Chronic ... diagnosis #algorithm #hepatology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
Multiple Myeloma ... diseases, CML, ... plasmacytoma, POEMs syndrome ... MGUS #diagnosis #hematology ... #oncology