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diagnosis rheumatology betadglucan differential galactomannan guidelines infectiousdiseases neurology physicalexam signs treatment abnormal anticoagulation antiphospholipid aps aspergillus atlas bcnie beaus behcet
Candidemia Workup and Management - IDSA Guidelines 1) Antibiotics • Empiric: Echinocandins (e.g. micafungin) for most patients
Candidemia Workup and Management ... week to assess ocular ... or TEE unless clinical ... #candida #candidiasis ... #treatment #fungal
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
• Pathogens: Candida ... cut-offs defined in clinical ... Clav (may be + as ... long as 5d after ... - Frozen ice-pops
Antiphospholipid Syndrome (APS) APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
Antiphospholipid Syndrome ... at least: • 1 clinical ... presence of 1 clinical ... present Treatment (EULAR ... #management #anticoagulation
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... ulceration • Ocular ... Medium and large also ... (Clinical Dx). ... #diagnosis #management
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Clinical Picture ... Ocular- 50%: Ptosis ... Generalized fatigue - ALS ... Bedside: ice pack ... Gravis #diagnosis #management
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives 1,3-Beta-D-Glucan • Cell wall component of many fungi
component of many fungi ... • Routine use: Candida ... cut-offs defined in clinical ... >90% (In most clinical ... Penicillium), Frozen ice-pops
Debridement and Management of Prosthetic Joint Infection (PJI) Duration of symptoms <3 weeks OR <30 days
Debridement and Management ... ) - Fungus: ... expectancy, poor candidacy ... Chalk Talks by Nico ... #Debridement #Management
Blood Culture-Negative Infective Endocarditis (BCNIE) Definition: No etiology found after 3 separate blood cultures remain negative for
fastidious bacteria or fungi ... antimicrobials, clinical ... (Aspergillus, Candida ... antiphospholipid syndrome ... specific pathogens also
Locked-in Syndrome (LiS) in ALS What happens when ALS patients opt for mechanical ventilation? They can become
Locked-in Syndrome ... locked in at the final ... #LockedIin #Syndrome ... #LiS #ALS #clinical ... #physicalexam #ocular
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 Esophageal Necrosis Etiology: - Ischemia and Gastric Outlet Obstruction with GERD may be inciting events - Associated
use, infections (Candida ... Stevens-Johnson syndrome ... Can also occur after ... restored to esophagus Clinical ... Necrosis #diagnosis #management
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