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management hematology anticoagulation antiphospholipid aps cryofibrinogenemia dermatology differential erythematosus guidelines hemeonc hemophagocytic hlh lymphohistiocytosis macrophage monoclonal oncology paraproteinemias polychondritis relapsing
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... Syndrome (MAS) ... SJIA], systemic lupus ... #Syndrome #Diagnosis ... #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Differential Diagnosis ... Clinical Features ... Chronic B-cell activation ... #Rheumatology
Antiphospholipid Syndrome (APS) APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
Antiphospholipid Syndrome ... antibodies (aPL): • Lupus ... at least: • 1 clinical ... presence of 1 clinical ... present Treatment (EULAR
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
myopathy • Anti MAG ... Hypergammaglobulinemic macular ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... #Differential #Diagnosis
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Cryofibrinogenemia Clinical ... pulmonary emboli, and ocular ... : • + Clinical ... Antiphospholipid syndrome ... #rheumatology #
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rheumatic pain Clinical ... : • A clinical ... diagnosis • Rule ... the collar bone ... #Rheumatology #
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
HLH is a critical ... (often termed MAS-HLH ... Syndrome) 3. ... Clinical Presentation ... #Management #Hematology
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
the most common clinical ... chondritis • Ocular ... : • Clinical tests ... Polychondritis #rheumatology ... #diagnosis #management
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