11 results
Nephron Remodeling as a Mechanism of Diuretic Resistance. When high doses of loop diuretics are used
used on a long-term ... , principal cells ... and intercalated cells ... #Pathophysiology ... NephronRemodeling #NEJM
Features of a Sickle Cell Crisis 
Sickle-cell disease - an autosomal recessive blood disorder.
Characterized by red
These cells can ... go on to block blood ... exclusively affects black ... The underlying pathophysiology ... Crisis #Features #Signs
Black Hairy Tongue- ...A polymicrobial wound infection developed, and she received treatment with intravenous meropenem and
Black Hairy Tongue ... Black discoloration ... in her mouth...Black ... and has no long-term ... #NEJM #photo #clinical
Scoliosis: Pathogenesis and clinical findings (Cobb Angle > 10 Degrees)

 • Incr Axial rotation of thoracic
findings (Cobb Angle ... joints to the pelvis ... -> The pelvis is ... #Scoliosis #pathophysiology ... msk #diagnosis #signs
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
various inflammatory cells ... histopathologic term ... especially knees and ankles ... HenochScholeinPurpura #Pathophysiology ... #Diagnosis #Signs
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... tissue: Epithelioid cells ... fever, malaise, lack ... Extrapulmonary: ankle ... Diagnosis #Management #Signs
Non-Infective Endocarditis (NBTE / Marantic Endocarditis)
Non-infective endocarditis is also known as: Non-bacterial thrombotic endocarditis (NBTE), Aseptic
heart valves • Lack ... Inflammatory cells ... pathognomonic signs ... Marantic #diagnosis #pathophysiology
Woltman's sign of hypothyroidism- ...At the time of presentation, a physical examination was notable for the
Woltman's sign of ... relaxation of the ankle ... video)...Woltman’s sign ... #clinical #photo ... #NEJM #Woltmans
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... with or without back ... • Bilateral signs ... Pleocytosis > 100 cells
Secondary Glaucoma: Pathogenesis and Clinical Findings
Open-Angle Secondary Glaucoma:
 • Pre-trabecular defect -> Aqueous outflow is obstructed
Findings Open-Angle ... pressure Closed-Angle ... retinal ganglion cells ... retinal ganglion cells ... Secondary #Glaucoma #pathophysiology