10 results
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... smear: Smudge cells ... or basket cells ... ’s lymphoma or acute ... Contamination, colitis
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
Acute Rheumatic ... B and CD-4+ T cells ... Prolonged PR Interval, Carditis ... #Acute #RheumaticFever ... pathophysiology #diagnosis #signs
Features of a Sickle Cell Crisis 
Sickle-cell disease - an autosomal recessive blood disorder.
Characterized by red
Characterized by red blood cells ... These cells can ... 2) Aplasia - Acute ... sequestration of sickle cells ... Crisis #Features #Signs
Mastoiditis: Pathogenesis and clinical findings

Acute or Chronic Otitis Media -> 
Stage 1: Hyperemeia of the mastoid
clinical findings Acute ... the mastoid air cells ... ) Stage 4: Cell ... larger & irregular cavities ... pathophysiology #signs
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
polymorphisms alter cell-mediated ... various inflammatory cells ... histopathologic term ... Pathophysiology #Diagnosis #Signs
Central Retinal Artery Occlusion: Pathogenesis and clinical findings
 • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
-> Endothelial cell ... lymphoma, sickle cell ... trucking" • Acute ... Retina • Ganglion cells ... ophthalmology #diagnosis #signs
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
tissue: Epithelioid cells ... and progressive Acute ... rarely preceded by acute ... Löfgren syndrome: ACUTE ... Diagnosis #Management #Signs
Pyoderma Gangrenosum in Ulcerative Colitis- ...left chest (Panel A) and leg (Panel B). The physical examination
in Ulcerative Colitis ... mixed inflammatory-cell ... #clinical #photo ... #NEJM #pyoderma ... #derm
Avascular Necrosis: Pathogenesis and Clinical Findings
 • Physical Trauma (esp. to the scaphoid bone with damage
) - Sickle-cell ... affected) - Acute ... hematopoietic marrow cells ... hypolucency "Crescent sign ... pathophysiology #diagnosis #signs
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
purpura: Strong sign ... CRP GCA (Giant Cell ... Multinucleated giant cells ... pulmonary infiltrates/cavities