7 results
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic inflammatory vasculitis ... Diagnosis = clinical ... systemic sx + signs ... them, but urgent rheumatology ... #Temporal #Signs
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
Pathogenesis and Clinical ... various inflammatory cells ... histopathologic term ... Pathophysiology #Diagnosis #Signs ... #Symptoms
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
purpura: Strong sign ... Elevated ESR and CRP GCA ... develop in pts with GCA ... • Progressive symptoms ... Differential #Diagnosis #Rheumatology
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
Related Disease Clinical ... No necrosis, No vasculitis ... supporting long-term ... management #phenotypes #workup ... #treatment #rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... meningitis), MCC CNS symptoms ... Behcet syndrome (Clinical ... diagnosis #management #signs ... #symptoms #rheumatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... with no early symptoms ... Physical Exam/Signs ... Contamination, colitis ... Leukemia #diagnosis #workup
When to look for clonal/neoplastic hypereosinophilia (HEo)?
 - Exclusion of frequent causes (Drug-induced HEo, helminthiasis, cancer,
) - Clinical symptoms ... BM biopsy (Mast cells ... HEON #Diagnosis #Signs ... #Hematology #Workup