11 results
Nephron Remodeling as a Mechanism of Diuretic Resistance. When high doses of loop diuretics are used
used on a long-term ... , principal cells ... and intercalated cells ... #Pathophysiology ... NephronRemodeling #NEJM
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
mutated in all cells ... Retinoblastoma Signs ... Retinoblastoma #pathophysiology ... #ophthalmology ... #diagnosis #signs
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... in literature (NEJM ... cases (Cornelia NEJM ... required +/- prompt ophthalmology ... GCA #Temporal #Signs
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
various inflammatory cells ... histopathologic term ... HenochScholeinPurpura #Pathophysiology ... #Diagnosis #Signs
Skin Mottling - Skin mottling, a common clinical sign in patients in shock, is a violaceous
common clinical sign ... B) #Clinical #Derm ... Hypoperfusion #Shock #NEJM
Central Retinal Artery Occlusion: Pathogenesis and clinical findings
 • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
Retina • Ganglion cells ... Occlusion #CRAO #pathophysiology ... #ophthalmology ... #diagnosis #signs
Evolution of Purpura Fulminans - On physical examination, he had small purpura on his legs (Panel
(Panel B), and signs ... #Clinical #Derm ... Meningococcemia #NEJM
Pemberton’s Sign in a Patient with a Goiter- Physical examination revealed an enlarged thyroid with no
Pemberton’s Sign ... Pemberton’s sign ... Pemberton’s sign ... #NEJM #Pembertons ... #sign #radiology
Woltman's sign of hypothyroidism- ...At the time of presentation, a physical examination was notable for the
Woltman's sign of ... video)...Woltman’s sign ... #clinical #photo ... #NEJM #Woltmans
Corrigan’s Pulse and Quincke’s Pulse- ...While the patient was sitting upright, the right carotid artery was
diastolic collapse — a sign ... pulsation — a sign ... #clinical #photo ... #NEJM #corrigans