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Prolonged neuromuscular blockade - Differential Diagnosis
- Drugs, Acid-base Disorders, Metabolic, Neurologic, Electrolyte abnormalities

By Mark Harris, MD
neuromuscular blockade ... MarkHarrisMD #nmb ... neuromuscular #blockade ... Anesthesiology #Causes
Antiarrhythmics - Vaughan Williams Classification
Class I (Ia, Ib, Ic) - Na+ Channel Blockade
 • Slows depolarization
- Na+ Channel Blockade ... Beta Receptor Blockade ... III - K+ Channel Blockade ... - Ca2+ Channel Blockade ... Classification #Classes
Neuromuscular Blockade (Paralytics) and Monitoring

Neuromuscular blockade caring for patients with severe ARDS and may reduce mortality.
Neuromuscular Blockade ... Neuromuscular blockade ... impairment • NMB ... ) - All NMBs are ... Neuromuscular #Blockade
Demyelinating Diseases - Differential Diagnosis
 • Inflammatory: MS, ADEM, NMO, Paraneoplastic, Sjogren's, Polyarteritis nodosa, SLE
 •
Inflammatory: MS, ADEM, NMO ... Differential #Diagnosis #causes
Treatment of NMS
 Dopamine antagonists should be discontinued immediately in patients suspected of NMS. Like SS,
Treatment of NMS ... patients suspected of NMS ... mainstay treatment of NMS ... considered in milder cases ... of NMS.
Train of Four (TOF) Monitoring - Neuromuscular Blockade

Used to titrate NMB to the minimum effective dose.
Neuromuscular Blockade ... Used to titrate NMB ... is documented, NMB ... Neuromuscular #Blockade ... #NMB #neurology
Hyperthermia Syndromes Comparison
Serotonin Syndrome - NMS - Malignant Hyperthermia - Malignant Catatonia
Cause - Onset - Vitals
Serotonin Syndrome - NMS ... Malignant Catatonia Cause
EEG/Bispectral Index (BIS) Monitoring - Neuromuscular Blockade

 • Use EEG/BIS monitor to ensure sedation depth is
Neuromuscular Blockade ... sedation during NMB ... reduces awareness of NMB ... Neuromuscular #Blockade ... #NMB #neurology
Internal Jugular Vein Rouleaux Flow on POCUS

Amazing video of a dilated IJV showing Rouleaux flow. Whenever
Rouleaux Flow on POCUS ... significantly, it causes ... echogenic as in this case ... for underlying cause ... Jugular #IJ #Vein #POCUS
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
CLASS 1A: Moderate Blockade ... CLASS 1B: Weak Blockade ... CLASS 1C: Strong Blockade ... Classification #Classes