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diagnosis hematology agglutinin algorithm anemia cold disease falsepositives fungal galactomannan hemolysis hemolytic hepatitis hepatology injury laboratory liver myopathy myositis rheumatology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Membrane): - Autoimmune ... Drug-associated, PCH ... Liver Disease, PNH ... Laboratory Tests
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Liver Injury - Differential ... HBV, HCV, HEV, EBV ... Celiac disease • Autoimmune ... : Autoimmune hepatitis ... extrahepatic source - Tests
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral infection, autoimmune ... - Mycoplasma, EBV ... younger pts) Differential ... • Diagnostic Test ... Donath-Landsteiner test
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives 1,3-Beta-D-Glucan • Cell wall component of many fungi
Other +s: PCP, Histo ... IA PPV NPV ... the use of this test ... in BAL does not differentiate ... blood products #BetaDGlucan
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential ... Diagnostic Tests ... • ANA < 20 % IBM ... Other Diseases: • PBC ... #rheumatology #differential
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