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diagnosis differential agglutinin autoimmune cold disease gap gca giantcell globulin hemolysis hemolytic management myopathy myositis protein proteingap rheumatology signs symptoms
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Drug-associated, PCH ... Liver Disease, PNH ... Defects: Sickle cell anemia ... Laboratory Tests ... Differential #Diagnosis #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
• Symptoms of anemia ... - Mycoplasma, EBV ... • Diagnostic Test ... Donath-Landsteiner test ... #hematology #diagnosis
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic complaints- anemia ... the “Chewing gum test ... in literature (NEJM ... cases (Cornelia NEJM ... them, but urgent rheumatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
acute HIV, HBV, EBV ... (RA, Temporal arteritis ... gastric tumors • Hematology ... Thalassemia, Sickle cell anemia ... differential #diagnosis #hematology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Diagnostic Tests ... • ANA < 20 % IBM ... • Nonerosive arthritis ... Other Diseases: • PBC ... Myositis #Myopathy #rheumatology
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