1180 results
What's in a Blood Gas? VBG vs ABG

BOTTOM LINE: VBG is less painful, more easily obtained
sensitivity & 100% NPV ... #EBM #Diagnosis
Goal-Directed Therapy - Evidence Summary of Major Clinical Trials

 - EGDT: NEJM 2001

 - ProCESS: NEJM
Trials - EGDT: NEJM ... - ProCESS: NEJM ... 2014 - ARISE: NEJM ... - ProMlSe: NEJM ... Therapy #Trials #EBM
PCI in Acute MI with Cardiogenic Shock. #EBM #Cardiology #CULPRITSHOCK #PCI #VisualAbstract #NEJM
#EBM #Cardiology ... VisualAbstract #NEJM
A Controlled Trial of Erenumab for Episodic Migraine #EBM #Neuro #Erenumab #Migraine #CGRP #VisualAbstract #NEJM
Episodic Migraine #EBM ... VisualAbstract #NEJM
Important Biostatistics and Epidemiology Equations

Sensitivity = TP / (TP + FN) = true positives / disease
#specificity #PPV ... #NPV
Trial of Solanezumab for Mild Dementia Due to Alzheimers Disease #EBM #Dementia #Solanezumab #Alzheimers #NegativeTrial #VisualAbstract
Alzheimers Disease #EBM ... VisualAbstract #NEJM
Fungal Biomarkers: Comparing Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 •
Spec -80% for IA, PPV ... < 50%, NPV > 90%
Glecaprevir and Pibrentasvir in Patients with HCV and Severe Renal Impairment #EBM #Hepatology #HCV #CKD #Glecaprevir
Renal Impairment #EBM ... VisualAbstract #NEJM
Acute Coronary Syndrome - Diagnostic Likelihood Ratios for Symptoms and Physical Examination. 

Source:  Does This
JAMA. 2015 Nov 10 ... #EBM #Diagnosis
An AAV5 vector with a functional factor VIII gene tested in men with hemophilia A #EBM
hemophilia A #EBM ... VisualAbstract #NEJM