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diagnosis differential oncology management algorithm leukemia workup aplastic arthritis blood cll disorders gout gravis joint lymphocytic markers mds monoarthritis monoarticular
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... petechiae Causes ... Sulfonamides - NSAIDs ... #oncology #hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Disorders - Markers and ... T-cell - CD7, CD3 Chronic ... Pelger-Huet, Macrocytic anemia ... Amy Chung, MD, MSc ... Blood #Disorders #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... skin that are caused ... Out Secondary Causes ... Marrow Failure • Chronic ... Syndromes #diagnosis #hematology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
noninflammatory Signs ... • Better with NSAIDs ... weeks) Can Be Caused ... Differential #Diagnosis #MSK ... #rheumatology #
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Physical Exam/Signs ... • Neutropenia, anemia ... leukemia #CLL #Chronic ... workup #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... with a relatively chronic ... -> AML: Blast crises ... - infiltrates (anemia ... #Leukemia #Hematology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Too many cells in ... Better call hematology ... normal/high - Chronic ... about secondary causes ... Algorithm #workup #hematology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
test - Cogan sign ... - Peek sign ... immunologic assay - MuSK ... inhibition - Chronic ... NSAIDs - Immunomodulating
Gout - Diagnosis and Management Summary 3 Conditions for Gout to Manifest: 1. Hyperuricemia 2. Monosodium urate deposition in
double contour sign ... Dual-energy CT → MSU ... intramuscular) • NSAIDs ... +Radiographic signs ... management #treatment #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... Multinucleated giant cells ... Eosinophilia, asthma, chronic ... often causes arthritis ... Differential #Diagnosis #Rheumatology
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