16 results
Gout (Gouty Arthritis) - MSK Radiology
Imaging Findings:
 • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
Gout (Gouty Arthritis ... These are CLASSIC gouty ... • Gouty tophus ... NO prior signs ... #rheumatology
Approach to Gout
Diagnosis: r/o septic arthritis! Needle-shaped, negative birefringent crystals
Treatment:
 • Weight loss, diet, d/c culprit
Approach to Gout ... medications • Acute: NSAIDs ... flares/year 2) Gouty ... NUIM_Chiefs #gout ... #ULT #rheumatology
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
double contour sign ... Dual-energy CT → MSU ... intramuscular) • NSAIDs ... +Radiographic signs ... #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
noninflammatory Signs ... • Better with NSAIDs ... Crystal induced (Gout ... fever • Lyme • Gout ... #rheumatology #
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
reactive arthritis, gout ... Spondyloarthropathies, gout ... Parallel, yellow = gout ... #Joint #Pain #MSK ... #rheumatology #
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
test - Cogan sign ... - Peek sign ... immunologic assay - MuSK ... NSAIDs - Immunomodulating ... diagnosis #management #neurology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
petechiae Causes ... Sulfonamides - NSAIDs ... megakaryocytes and ... aplastic anemia Treatment ... Anemia #oncology #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
immature blasts and ... high WBC count cause ... WBC >100k, + lab signs ... Lysis of tumor cells ... diagnosis #management #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
anemia DDX: Rule Out ... factor (GCSF) treatments ... marrow studies Treatment ... Immunosuppressive treatment ... Syndromes #diagnosis #hematology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
diagnosis • Rule out ... other causes such ... lower jaw Treatment ... manifestations: NSAIDs ... SAPHO #Syndrome #Rheumatology