13 results
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophilia, 500-1,500 cells ... for secondary causes ... eosinophilia (common causes ... organ-specific signs ... Differential #diagnosis #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
and petechiae Causes ... Sulfonamides - NSAIDs ... number of CD34+ cells ... number of CD34+ cells ... Anemia #oncology #hematology
Gout (Gouty Arthritis) - MSK Radiology
Imaging Findings:
 • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
Gouty Arthritis) - MSK ... Case description ... mass and NO prior signs ... - **MSK rads ... #rheumatology
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
an underlying cause ... Too many cells in ... Better call hematology ... about secondary causes ... Algorithm #workup #hematology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
noninflammatory Signs ... • Better with NSAIDs ... weeks) Can Be Caused ... Differential #Diagnosis #MSK ... #rheumatology #
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... WBC >100k, + lab signs ... Lysis of tumor cells ... diagnosis #management #hematology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
test - Cogan sign ... - Peek sign ... immunologic assay - MuSK ... : Steroids and NSAIDs ... diagnosis #management #neurology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... Xerostomia • Dental caries ... Nephrogenic DI Hematologic ... phenomenon (16%) MSK ... Sjogrens #Syndrome #Rheumatology
When to look for clonal/neoplastic hypereosinophilia (HEo)?
 - Exclusion of frequent causes (Drug-induced HEo, helminthiasis, cancer,
Exclusion of frequent causes ... BM biopsy (Mast cells ... HEON #Diagnosis #Signs ... #Hematology #Workup
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
10-33% develop MS ... • Bilateral signs ... Pleocytosis > 100 cells ... • Infectious causes ... diagnosis #management #neurology