15 results
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... cases/100,000 per year ... axonal form • MRI ... #management #treatment ... #neurology
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Demyelinating Disease (MS ... Poliomyelitis, Guillain-Barre ... multiplex, Phrenic ... Weakness #Causes #differential ... #diagnosis #neurology
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... • Lhermitte’s sign ... resonance imaging [MRI ... sclerosis #diagnosis #management ... #neurology #treatment
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... per 100,000 per year ... - Spinal MRI may ... #Syndrome #diagnosis ... #management #neurology
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
constipation Differential ... cord • Guillain-Barre ... • Multiple sclerosis ... Imaging studies: • MRI ... #differential #
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
Brain, Eye, and Ear ... neuropathy (LHON) plus MRI ... consistent with MS ... #neurology #noninflammatory ... #differential #
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
• Bilateral signs ... suggestive of multiple ... Demyelination: - Multiple ... Myelitis #diagnosis #management ... #neurology #differential
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
life-threatening Differential ... - Peek sign ... : Steroids and NSAIDs ... Gravis #diagnosis #management ... #neurology
One and a Half Syndrome on Physical Exam

This 28 year old patient presented to clinic with
One and a Half Syndrome ... , strokes, and multiple ... MRI was ordered ... diagnosed with MS ... ophthalmology #neurology
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Weakness - Differential ... • Mononeuritis multiplex ... Lack of UMN/LMN signs ... EMG) studies • MRI ... #Diagnosis #neurology