34 results
Buprenorphine-Naloxone and treatment of withdrawal symptoms

Prerequisites for starting Suboxone in the ED:

1. Patient has an opioid
Buprenorphine-Naloxone ... and treatment of withdrawal ... Suboxone #Opioid #Withdrawal ... Algorithm #Management #Addiction
Opioid Overdose Management and Discharge Criteria

Patients with presumed opioid overdose were safely discharged one hour after
one hour after naloxone ... Criteria #Opiate #Narcan ... #Naloxone #Addiction
ED-Bridge Buprenorphine Algorithm for management of acute opiate withdrawal in the ED

#Management #Opioid #Withdrawal #Emergency #Buprenorphine
of acute opiate withdrawal ... Management #Opioid #Withdrawal ... Treatment #Algorithm #Addiction
Comparison of Opioid Withdrawal Profiles

#Opioid #Withdrawal #Pharmacology #Diagnosis #Addiction #Halflife #Timeline #Windows
Comparison of Opioid Withdrawal ... Profiles #Opioid #Withdrawal ... Pharmacology #Diagnosis #Addiction
Opioid Withdrawal Symptom Timeline
Stage l: Up to 8 hours 
Stage II: 8—24 hours 
Stage Ill: Up
Opioid Withdrawal ... days #Opioid #Withdrawal ... #Progression #Addiction
COWS Clinical Opiate Withdrawal Scale
Score: 
5-12 mild; 13-24 moderate; 25-36 moderately severe; more than 36 =
Clinical Opiate Withdrawal ... than 36 = severe withdrawal ... #Diagnosis #Addiction ... #COWS #Opiate #Withdrawal
Buprenorphine Induction Algorithm

#Management #Pain #Withdrawal #Buprenorphine #Induction #Algorithm #Addiction #Prescribing
Management #Pain #Withdrawal ... Induction #Algorithm #Addiction
Trick of the Trade: Naloxone Dilution for IV Use - Given that many ED overdose patients
of the Trade: Naloxone ... opioid-naive, lower naloxone ... and administer naloxone ... chances of severe withdrawal ... or syringe of naloxone
Addictions: Pathogenesis

Mesolimbic Dopaminergic Pathway:
 • Dopaminergic neurons in Ventral Tegmental Area (VTA) in midbrain under continuous
Addictions: Pathogenesis ... which influence addictive ... behaviours -> Addiction ... Tolerance and Withdrawal ... ) #Drug #Addiction
Naloxone - Toxicology

Adult starting dose:
 - 0.4 mg IV/IM/IO/SQ for non-opioid dependent patients
 - 0.04 mg
Naloxone - Toxicology ... after 10-12 mg naloxone ... the effective* naloxone ... A naloxone infusion ... #Narcan #Toxicology