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dm2 dosing insulin kdigo management medications table acei algorithm arb based comparison diabetic estimation gfr hypoglycemics impairment initiation renal sulfonylureas
Management of Diabetes Mellitus in Patients With CKD 1. Monitor for changes in BP, serum creatinine, &
Patients With CKD ... patients with T2D, CKD ... and CKD should ... #Diabetes #CKD # ... ADA #KDIGO #eGFR
Summary of dosing recommendations in renal impairment of commonly used hypoglycaemic agents #Diabetes #Diabetic #Medications #Pharmacology #Dosing
Summary of dosing ... #Diabetic #Medications ... #Pharmacology # ... Renal #Impairment #CKD ... #Table #GFR #Hypoglycemics
Diabetes Medications Summary Table Insulin Lifestyle modifications Metformin Sulfonylureas GLP-1 receptor agonists - ↓ major adverse CV events TZDs DPP-4 inhibitors SGLT2 inhibitors -
Diabetes Medications ... Summary Table ... modifications Metformin ... Improved outcomes in CKD ... comparison #management #endocrinology
Metformin in Diabetic Kidney Disease Immediate release: • Initial 500 mg or 850 mg once daily •
Metformin in Diabetic ... maximum dose eGFR ... recommended dose eGFR ... < 30: Stop metformin ... #CKD #pharmacology
Metformin Pharmacology Summary Mechanisms of Action: • Suppresses gluconeogenesis by the liver • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... Summary Mechanisms ... #Pharmacology # ... Summary #DM2 #diabetes ... #endocrinology
Sulfonylureas - Pharmacology Summary Mechanisms of Action: Binds to the ATP-sensitive potassium channel in pancreatic beta cells,
Sulfonylureas - Pharmacology ... Summary Mechanisms ... contraindicated in CKD ... #Summary #DM2 # ... diabetes #endocrinology
Estimating the Total Daily Dose (TDD) of Insulin: Weight-Based Dosing TDD in units of insulin = N
(stage IV or V CKD ... Add sliding scale ... Weight #Based #pharmacology ... #endocrinology ... #diabetes #DM2
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