146 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
and Nephrotic Syndromes ... Nephritic syndrome—due ... RBC casts in urine ... but in severe cases ... Nephritic #Nephrotic #Syndromes
Causes of Secondary Hypertension - Differential Diagnosis and Screening Testing
Common causes: 
 • Renal parenchymal disease
Causes of Secondary ... Testing Common causes ... standard conditions (supine ... • Cushing’s syndrome ... Mineralocorticoid excess syndromes
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
1ml blood/liter urine ... disease - Alport syndrome ... pain hematuria syndrome ... disease Renal Causes ... • Nutcracker syndrome
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Nephritic vs Nephrotic Syndrome ... nephrotic/nephritic syndromes ... hematuria (RBC casts ... dysmorphic RBCs in urine ... Nephritic #Nephrotic #Syndrome
Causes Abnormal Urine Color - Differential Diagnosis
Turbid White Urine (Albinuria):
 • Chyluria, Filariasis, Schistosomiasis, Malignancy, Phosphaturia,
Causes Abnormal ... • Drummond's syndrome ... (blue diaper syndrome ... Bag Syndrome - ... UTI caused by (Proteus
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
Urine chloride < 20 mmol/l - Chloride responsive (Chloride
Causes of Metabolic ... diuretic use Urine ... BP = Bartter's Syndrome ... , Gitelman's Syndrome ... Metabolic #Alkalosis #Causes
Blood gas analysis
Metabolic alkalosis
Measured urine CI
< 10 mEq/L
Saline responsive
> 10 mEg/L
Not saline responsive
- Vomiting or NG
CI < 10 mEq/L Saline ... suction Endocrine cause ... H+ loss Renal cause ... diuretics - Bartter syndrome ... - Gitelman syndrome
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... Proteinuria (Negative urine ... • Fanconi's syndrome ... sediment - WBC/RBC casts ... Diagnosis #Algorithm #Causes
Causes of Generalized Edema - Differential Diagnosis Algorithm
Overfill (Increased renal sodium retention, Urine Na > 40meq/L)
Causes of Generalized ... sodium retention, Urine ... • Nephrotic Syndrome ... • Nephrotic syndrome ... Diagnosis #Algorithm #Causes
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
hyperaldosteronism • Low Urine ... (late) • High Urine ... , Gitelman Syndrome ... , Liddle syndrome ... Algorithm #Nephrology #Causes