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hematology anemia rheumatology agglutinin aiha autoimmune brca breast cancer causes compared cryofibrinogenemia disease erythemas extravascular hemolysis indications infections infectiousdiseases intravascular
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table Warm AIHA (48-70%) Cold AHA (16-32%) • Donath-Landsteiner HA (paroxysmal
Autoimmune Hemolytic ... Diagnosis Table ... AIHA (7-8%) DAT-negative ... #Diagnosis #Table ... #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Autoimmune (AIHA)"Cold ... usually IgM) (e.g. primary ... Extravascular #Causes #differential ... #diagnosis #hematology
Who to test for BRCA 1/2? Female Breast Cancer: • ≤ 45-50 years at diagnosis • Triple
45-50 years at diagnosis ... • Triple Negative ... cancers in this table ... factors in this table ... #indications #oncology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
15% of AIHA Primary ... Diagnosis: • hemolytic ... for anti-C3d and negative ... younger pts) Differential ... #anemia #hematology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Primary (essential ... Cryofibrinogenemia Diagnosis ... levels >1g/L • Negative ... cryoglobulins • Negative ... Cryofibrinogenemia #diagnosis
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... purple, hemorrhagic skin ... /Quantity: • Primary ... DIC/TTP/HUS - Hemolytic ... #Diagnosis #hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Alpha & Mu) Skin ... • Coombs (-) hemolytic ... anemia due to cold ... #Monoclonal #Differential ... #Diagnosis #Oncology
Scleroderma Like Conditions - Differential Diagnosis Eosinophilic Fasciitis: - Orange peel induration (peau d'orange) of proximal extremities
Like Conditions - Differential ... Diagnosis Eosinophilic ... #Scleroderma #Differential ... #Diagnosis #comparison ... #table #dermatology
Waterborne Infections - Differential Diagnosis Framework Infections that can be acquired from fresh water, brackish water, sea
Diagnosis Framework ... • Escherichia coli ... toxin-producing) and Hemolytic ... Blooms (HABs) Skin ... CNS Infection • Primary
Erythemas Summarized Erythema ab igne • A dermatosis that results from repeated exposure to heat (fires, heating
centrifugum • A chronic skin ... gyratum repens • A skin ... PrathitKulkarni #Erythemas #comparison ... #table #differential ... #diagnosis #dermatology
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