15 results
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Maculopapular rash ... reticularis Differential ... • Goodpasture syndrome ... #dermatology #rash ... #diagnosis #rheumatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Sarcoidosis • GPA ... Antiphospholipid-antibody syndrome ... Sarcoidosis #dermatology ... #rashes #differential ... #diagnosis #rheumatology
Approach to the Rash in a an oncology patient - MINT-C Mnemonic
M - Malignancy: Leukemia cutis,
Dermatoses: Sweet Syndrome ... dermatoses #skin ... #Rash #oncology ... #differential # ... MINTC #Mnemonic #dermatology
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
- Differential ... - GPA Cutaneous ... Disease • Cogan syndrome ... #dermatology #rheumatology ... #differential #
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... purple, hemorrhagic skin ... vasculitis - GPA ... #Diagnosis #hematology ... #nonpalpable #dermatology
DRESS Syndrome vs SJS/TEN
DRESS
 • Latency: 2-8 weeks
 • Rash: Morbilliform
 • Mucosal involvement: 50% have
DRESS Syndrome vs ... : 2-8 weeks • Rash ... : 4-28 days • Rash ... #SJS #TEN #comparison ... #table #dermatology
Pustular Skin Lesions - Differential Diagnosis Framework

What are pustules?
• Pustules < 5-10 mm + pus
• Material
- Differential ... Generalized itchy rash ... SAPHO syndrome ( ... Sweet syndrome ... #Diagnosis #Dermatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitides - Differential ... > PR3 60% • GPA ... mucositis - Rash ... • ANCA (Dx: GPA ... #diagnosis #rheumatology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
Look for gamma gap ... Causes of false- negative ... plasmacytoma, POEMs syndrome ... MGUS #diagnosis #hematology ... #oncology
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
Bernard-Soulier Syndrome ... Grey Platelet Syndrome ... Platelet #Defects #comparison ... #table #differential ... #diagnosis #hematology